Deviating samples can be defined as those which are not (correctly) cared for, for example they may have exceeded their maximum holding time, have not been retained at appropriate temperature, are presented in inappropriate containers/packaging, have inappropriate headspace, be denatured through heat, light or humidity, have deteriorated chemically or microbiologically, have become cross contaminated, been damaged in transit, have been supplied in insufficient quantity (or with incorrect dimensions) and so on. Such deviating samples may jeopardise the validity of the reported test or calibration result.